Pharma 11 Twin-Screw Compounder
The Thermo Scientific Pharma 11 is a very small-scale extruder perfect for a wide range of drug development applications. Achieving a minimum throughput of just 20 g/h, it is ideal for research and development applications especially when developing and testing recipes with expensive API and associated compounds. As a GMP compliant unit, the Thermo Scientific Pharma 11 is also suitable for clinical trials and small-scale production for throughputs up to 2.5 kg/h.
Designed to meet the toughest of challenges faced by customers and at the same time maximize the investment when progressing through the phases of the product development cycle, the screw, and barrel designs are geometrically scalable across the whole Thermo Scientific portfolio of extruders from lab and pilot through to production scale.
Designed to meet the toughest of challenges faced by customers and at the same time maximize the investment when progressing through the phases of the product development cycle, the screw, and barrel designs are geometrically scalable across the whole Thermo Scientific portfolio of extruders from lab and pilot through to production scale.
Features
Specifications
Features
Key Benefits:
– Small
– Small
- Uses smaller material quantities for faster, cost-effective development
- Maximizes lab space with a small footprint machine
- Perfect for the glove box or isolator applications due to removable touch screen
- Easy cleaning and validation: all material contact parts easily removable
- Easy to operate with the user-friendly, intuitive touchscreen with integrated feeder control
- 2-in-1 machine: easily convertible from hot-melt extrusion (HME) to twin-screw granulation (TSG) applications
- Minimizes scale-up risks: Cost and time saving due to the full scalability of the Thermo Scientific extruder product family
- Provides process control: Documentation of extrusion parameters and suitable for PAT
- GMP-compliant, full validation available: FAT, SAT, IQ/OQ
Specifications
Recommended for | – Research and discovery – Phase 1 |
Suitable for | – Co-extrusion – Sheet extrusion – Implant production |
Downstream options |
– Conveyor belt – Pelletizer |
Typical throughput HME | 20 g/h – 2.5 kg/h |
Typical throughput TSG | Up to 3 kg/h |
Unit type | Benchtop model |
Screw design | Parallel, co-rotating |